Is PRF the same as PRP?

They are related. PRP is platelet-rich plasma, prepared with an anticoagulant. PRF is spun without one, so it forms a fibrin scaffold that releases growth factors gradually rather than immediately. Both are autologous — derived from your own blood.

Is there a rejection risk?

No. The material comes from your own blood, which is the main reason its safety profile is favourable. Normal injection-related risks still apply and are discussed beforehand.

PRF Regenerative Therapy

Platelet-rich fibrin is prepared from a small sample of your own blood, spun to concentrate platelets and the growth factors they carry. In the jaw joint it is used to support repair in tissue that is inflamed or degenerating, most often alongside a joint procedure rather than as a treatment on its own.

How it is prepared and used

Blood is drawn as it would be for any blood test and spun in a centrifuge. Because no anticoagulant is used, the platelets form a fibrin matrix that releases growth factors over time rather than all at once. That concentrate is then introduced into the joint space, usually in combination with joint lavage or as part of a wider treatment sequence.

Who it tends to suit

It is most often considered for joints with persistent inflammation or early degenerative change that have not settled with load reduction and appliance therapy alone. It is not a first-line treatment, and it is not a substitute for addressing what is overloading the joint — introducing growth factors into a joint that is still being overloaded every night is treating the consequence.

An honest read of the evidence

Research on autologous blood concentrates in the temporomandibular joint is growing and broadly encouraging, particularly for pain and range of motion, but the studies are mostly small and protocols differ between them. It is reasonable to describe it as a promising adjunct with a strong safety profile, because the material is your own. It is not reasonable to present it as established or guaranteed, and we do not.

Common questions

Is PRF the same as PRP?: They are related. PRP is platelet-rich plasma, prepared with an anticoagulant. PRF is spun without one, so it forms a fibrin scaffold that releases growth factors gradually rather than immediately. Both are autologous — derived from your own blood.
Is there a rejection risk?: No. The material comes from your own blood, which is the main reason its safety profile is favourable. Normal injection-related risks still apply and are discussed beforehand.

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Patients of Dr. Samadian

Written by patients treated across the Dion Health practices.

“I found myself dealing with a number of medical issues that I had no idea were so directly tied to my sense of oral wellbeing. The professionals at Dion Health helped me resolve my clenching and grinding, leading to better sleep and a more enjoyable lifestyle.”
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